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Mortality in CHD-Related HF in Children

Am Heart J; ePub 2018 Dec 5; Burstein, et al

Advanced heart failure (AHF) in children with congenital heart disease (CHD) is uncommon but increasing and is associated with significant morbidity, mortality, and resource utilization, a recent study found. All hospitalization in the Pediatric Health Information System database involving patients aged ≤21 years with a CHD diagnosis and HF requiring at least 7 days of continuous inotropic support between 2004 and 2015 were included. Researchers found:

  • Of 485,482 CHD hospitalization, AHF was present in 2,712 (0.6%).
  • Approximately 1 in 5 children do not survive to hospital discharge.
  • Over the 11-year study period, despite the significant increase in CHD-related AHF hospitalizations, hospital mortality increased.
  • Median hospital costs were $252,000, a 6-fold increase above those without AHF.


Burstein DS, Shamszad P, Dai D, et al. Significant mortality, morbidity and resource utilization associated with advanced heart failure in congenital heart disease in children and young adults. [Published online ahead of print December 5, 2018]. Am Heart J. doi:10.1016/j.ahj.2018.11.010.