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Adverse HF Outcomes in Persons Living with HIV

Am Heart J; ePub 2019 Jan 11; Alvi, Afshar, et al

There is an increased 30-day heart failure (HF) readmission rate among persons living with HIV (PLHIV), a new study found. The cohort included 2,308 individuals admitted to a US tertiary medical center with decompensated HF. Researchers compared baseline characteristics, 30-day HF readmission, cardiovascular (CV), and all-cause mortality among PLHIV with HF vs individuals without HIV with HF. They found:

  • There were 374 (16%) PLHIV with HF; groups were similar with respect to age, sex, race/ethnicity, and CV risk factors.
  • PLHIV had increased 30-day HF readmission, CV, and all-cause mortality rates.
  • Conversely, PLHIV with a higher CD4 count and undetectable viral load (VL) had similar HF outcomes to uninfected controls.


Alvi RM, Afshar M, Neilan AM, et al. Heart failure and adverse heart failure outcomes among persons living with HIV in a US tertiary medical center. [Published online ahead of print January 11, 2019]. Am Heart J. doi:10.1016/j.ahj.2019.01.002.