Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Algorithm ruled out PE, averts radiation exposure in pregnant women

Key clinical point: A diagnostic algorithm adapted from a previous study safely ruled out acute pulmonary embolism in pregnant women with suspected pulmonary embolism.

Major finding: One of 477 patients (0.21%) had a diagnosis of symptomatic DVT in follow-up despite a negative result on the modified YEARS algorithm.

Study details: A prospective study of approximately 500 women with suspected PE managed at one of 18 European centers.

Disclosures: The study was supported by unrestricted grants from Leiden University Medical Center and 17 other participating hospitals. Many authors reported financial ties to the pharmaceutical industry.