Clinical Edge

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COVID-19 may increase risk of preterm birth and cesarean delivery

Key clinical point: Hospitalized pregnant women with COVID-19 appear to be at increased risk for preterm birth and cesarean delivery.

Major finding: Among 57 hospitalized patients with SARS-CoV-2 infection who underwent vaginal or cesarean delivery, 7 (12%) had spontaneous preterm or respiratory-indicated preterm delivery, compared with 7% who had preterm delivery in 2019. The cesarean delivery rate also was elevated (39% vs. 27% in the same area in 2019).

Study details: A prospective study of 77 women with laboratory-confirmed SARS-CoV-2 infection admitted during pregnancy or the immediate postpartum period in 12 maternity hospitals in northern Italy between Feb. 23 and March 28, 2020.

Disclosures: One author disclosed receiving funds from Lo Li Pharma and Zambongroup. The other authors did not report any potential conflicts of interest.


Savasi VM et al. Obstet Gynecol. 2020 May 19. doi: 10.1097/AOG.0000000000003979.