Key clinical point: A 29-item genetic risk score improved the screening pick-up rate for abdominal aortic aneurysms when used with age and sex.
Major finding: The polygenic risk score identified an AAA prevalence of 8.6% in men aged older than 50 years.
Study details: Researchers used data collected in the Million Veteran Program to derive the polygenic risk score.
Disclosures: The study had no commercial funding. Dr. Klarin has been a consultant to Regeneron.
Klarin D et al. Vascular Discovery 2020, abstract 170.