Clinical Edge

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Low fitness level linked to higher risk of heart failure in diabetes

Key clinical point: Lower fitness at baseline was more strongly associated with the risk of HFpEF vs. HFrEF.

Major finding: A 10% decline in fitness over the 4 years of follow-up was associated with a 11% increase in the overall risk of heart failure (hazard ratio, 1.11).

Study details: An ancillary study of 257 incident heart failure events from the LookAHEAD trial.

Disclosures: Dr. Pandey reported having no financial disclosures.


Pandey A et al. Epi/Lifestyle 2020, Abstract 16.