Clinical Edge

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CV health in pregnancy improves outcomes for mother and infant

Key clinical point: More favorable levels of gestational cardiovascular health (CVH) were associated with healthier obstetric and neonatal outcomes in a multinational cohort.

Major finding: Odds ratios per 1-point higher (better) CVH score were 0.61 (95% confidence interval, 0.53-0.70) for preeclampsia, 0.85 (95% CI, 0.76-0.95) for unplanned primary cesarean section (among primiparous mothers), 0.83 (95% CI, 0.77-0.91) for large for gestational age infant, and 0.79 (95% CI, 0.72-0.87) for infant insulin sensitivity index below the 10th percentile.

Study details: An analysis of 2,230 mother-child dyads from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.

Disclosures: Dr. Perak reported having received grant support from the National Heart, Lung, and Blood Institute; the American Heart Association; and from Northwestern University. The HAPO Study was supported by the National Heart, Lung, and Blood Institute and the National Institute of Diabetes and Digestive and Kidney Diseases.


Perak AM et al. Epi/Lifestyle 2020, Abstract 33.