Clinical Edge

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CV health in pregnancy improves outcomes for mother and infant

Key clinical point: More favorable levels of gestational cardiovascular health (CVH) were associated with healthier obstetric and neonatal outcomes in a multinational cohort.

Major finding: Odds ratios per 1-point higher (better) CVH score were 0.61 (95% confidence interval, 0.53-0.70) for preeclampsia, 0.85 (95% CI, 0.76-0.95) for unplanned primary cesarean section (among primiparous mothers), 0.83 (95% CI, 0.77-0.91) for large for gestational age infant, and 0.79 (95% CI, 0.72-0.87) for infant insulin sensitivity index below the 10th percentile.

Study details: An analysis of 2,230 mother-child dyads from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.

Disclosures: Dr. Perak reported having received grant support from the National Heart, Lung, and Blood Institute; the American Heart Association; and from Northwestern University. The HAPO Study was supported by the National Heart, Lung, and Blood Institute and the National Institute of Diabetes and Digestive and Kidney Diseases.

Citation:

Perak AM et al. Epi/Lifestyle 2020, Abstract 33.