Clinical Edge

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COACT: No benefit of immediate PCI for non–ST-elevation cardiac arrest at 1 year

Key clinical point: Early coronary angiography doesn’t improve 1-year outcomes, compared with delayed angiography following restoration of spontaneous circulation after out-of-hospital cardiac arrest without ST elevation.

Major finding: The 1-year survival after cardiac arrest without STEMI was 61.4% with immediate coronary angiography and not significantly different at 64% with delayed angiography.

Study details: The 19-center COACT trial randomized 552 Dutch patients to immediate or delayed coronary angiography following restoration of spontaneous circulation after out-of-hospital cardiac arrest without ST-elevation MI.

Disclosures: The presenter reported having no financial conflicts regarding the COACT trial, funded by the Netherlands Heart Institute and unrestricted research grants from Biotronik and AstraZeneca.

Citation:

Lemkes J. AHA 2019, Late-breaking Science session 4.