Key clinical point: Overweight in male teens predicts subsequent cardiomyopathy. The association increases with BMI and is strongest for dilated cardiomyopathy.
Major finding: Over a median of 27 years of follow-up, the hazard ratio for dilated cardiomyopathy in adulthood was 1.38 when adolescent body mass index was 22.5-25.0 kg/m2, using a BMI of 18.5-20.0 as the reference group. At a BMI over 35, the hazard ratio reached 8.11.
Study details: A nationwide, prospective registry cohort study of 1.67 million adolescent males in Sweden.
Disclosures: Funders included the Swedish government; Swedish Research Council; Swedish Heart and Lung Foundation; and Swedish Council for Health, Working Life and Welfare. The researchers reported having no conflicts of interest.
Robertson J et al. Circulation. 2019 May 20.