Clinical Edge

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Used together, troponin and coronary calcium improve CV risk assessment

Key clinical point: As cardiovascular risk predictors, troponin and coronary calcium have complementary value and function best together.

Major finding: The rates of ASCVD at 10 years were 2.4% when both biomarkers were negative but up to 9.8% when one was positive.

Data Source: Longitudinal cohort study of 6,749 participants in the Multi-Ethnic Study of Atherosclerosis, with a median 15 years of follow-up.

Disclosures: The senior investigator, Dr. Jaffe, has consulting relationships with many pharmaceutical companies.


Sandoval Y et al. J Am Coll Cardiol. 2020;76:357-70.