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Is Risk of Heart Failure After AF Declining?

Heart Rhythm; ePub 2017 Jan 21; Chamberlain, et al

The rates of heart failure (HF) following incident atrial fibrillation (AF) have not declined, according to a community study assessing trends overall and by ejection fraction. The community cohort included patients with incident AF from 2000 to 2013 with Cox regression examining the association of year of AF diagnosis with HF and the predictors of developing HF after AF. Researchers found:

  • Among 3,491 patients without prior HF, 759 (21%) developed incident HF over a mean follow-up of 3.7 years.
  • 422 (61%) patients with an echocardiogram had HF with preserved ejection fraction (HFpEF) and 270 (39%) had HF with reduced ejection fraction (HFrEF).
  • After adjustment, the risk of developing HF did not change over time per year of AF diagnosis: HR, 1.01 overall; 1.00 for HFpEF, 1.00 for HFrEF.
  • Increased age, obesity, smoking, diabetes, chronic pulmonary disease, and renal disease were predictors of developing HF.

Citation:

Chamberlain AM, Gersh BJ, Alonso A, et al. No decline in the risk of heart failure following incident atrial fibrillation: A community study assessing trends overall and by ejection fraction. [Published online ahead of print January 21, 2017]. Heart Rhythm. doi:10.1016/j.hrthm.2017.01.031.