Clinical Edge

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Predicting Risk of AF with AHA’s LS7 Score

Am J Cardiol; ePub 2017 Oct 19; Garg, et al

Better cardiovascular (CV) health is associated with a reduction in the development of atrial fibrillation (AF), according to an analysis using the American Heart Association’s (AHA) Life Simple 7 (LS7) metrics. The analysis included 9,756 participants (mean age 63 ±8.4 years, 57% women, 30% black) from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study who were free of AF at baseline and completed a follow-up exam 9.4 years later. An overall LS7 score was calculated at baseline as the sum of the LS7 component scores and classified as inadequate (0-4), average (5-9), or optimal (10-14) CV heath. The primary outcome was incident AF. Researchers found:

  • 725 incident AF cases were identified.
  • Compared to the inadequate category (n=534), participants in the optimal category (n=1,953) had a 32% lower odds of developing AF (OR, 0.68).
  • A 1-point higher LS7 score was associated with a 5% lower odds of incident AF (OR, 0.95).

Citation:

Garg PK, O’Neal WT, Ogunsua A, et al. Usefulness of the American Heart Association’s Life Simple 7 to predict the risk of atrial fibrillation (From the Reasons for Geographic and Racial Differences in Stroke [REGARDS] Study). [Published online ahead of print October 19, 2017]. Am J Cardiol. doi:10.1016/j.amjcard.2017.09.033.