Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Mortality & CVE After HRDM Procedures

Circulation; ePub 2017 Oct 18; Lee, Ling, et al

Approximately half of the deaths directly related to a heart rhythm disorder management (HRDM) procedure were among patients undergoing device implantation procedures, with cardiac tamponade being the most common cause of death. This according to a retrospective study of 48,913 patients undergoing HRDM procedures between January 2000 and November 2016 at the Mayo Clinic. Patients from all 3 tertiary academic centers were included. Researchers found:

  • Patients (mean age 65.7 years, 64% male) underwent a total of 62,065 HRDM procedures.
  • Overall mortality and cerebrovascular event (CVE) rate was 0.36% and 0.12%, respectively.
  • Among patients undergoing HRDM procedures, 48% of deaths directly related to the HRDM procedure were among patients undergoing device implantation procedures.
  • Overall, cardiac tamponade was the most frequent direct cause of death (40%); infection was the most common indirect cause of death (29%).
  • Overall 30-day mortality rate was 0.76%.

Citation:

Lee JZ, Ling J, Diehl NN, et al. Mortality and cerebrovascular events following heart rhythm disorder management procedures. [Published online ahead of print October 18, 2017]. Circulation. doi:10.1161/CIRCULATIONAHA.117.030523.