Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Catheter Ablation for AF in Adults with CHD

Heart Rhythm; ePub 2018 Dec 26; Liang, et al

In adults with congenital heart disease (CHD), catheter ablation for atrial fibrillation (AF) is safe and effective, even among patients with the most complex forms of CHD. This according to a multicenter retrospective analysis performed of adult CHD patients undergoing AF ablation. Researchers aimed to examine safety and efficacy and efficacy of AF ablation in this study group. Patients were divided into 3 groups (simple, moderate, and severe) based on CHD complexity. They found:

  • Overall, 84 CHD patients (mean age 51 years, 65.5% male, 45.2% with paroxysmal AF) undergoing AF ablation were included.
  • Pulmonary vein isolation (PVI) was performed in 80 (95.2%) patients, with 30 (35.7%) patients undergoing PVI alone.
  • Overall, complete and complete/partial freedom was achieved at 1 year in 53.1% and 71.6%, with no significant differences between those with simple, moderate, or severe complexity.
  • There were no major complications during follow-up.


Liang JJ, Frankel DS, Parikh V, et al. Safety and outcomes of catheter ablation for atrial fibrillation in adults with congenital heart disease: A multicenter registry study. [Published online ahead of print December 26, 2018]. Heart Rhythm. doi:10.1016/j.hrthm.2018.12.024.