Clinical Edge

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Severe COVID-19 may lower hemoglobin levels

Key clinical point: The hemoglobin value was significantly lower in severe COVID-19 patients, compared with those with milder forms.

Major finding: A weighted mean difference in hemoglobin content of −7.1 g/L (95% CI, −8.3 g/L to −5.9 g/L) was found in comparing severe to milder cases of COVID-19.

Study details: Meta-analysis of four studies of 1,210 COVID-19 patients with assessable hemoglobin values.

Disclosures: The authors declared that they had no conflicts of interest.


Lippi G et al. Hematol Transfus Cell Ther. 2020 Apr 11; doi:10.1016/j.htct.2020.03.001.