Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Why STEMI patients benefit from PCI of nonculprit lesions

Key clinical point: A new intracoronary imaging study provides a pathophysiological explanation for the observed benefit of complete revascularization in ST-elevation MI patients with multivessel disease and nonculprit obstructive lesions.

Major finding: Nearly half of ST-elevation MI patients with multivessel coronary artery disease had a nonculprit obstructive lesion with vulnerable plaque morphology.

Study details: This study involved identification of vulnerable plaque by optical coherence tomograpy in the nonculprit obstructive and nonobstructive coronary lesions of 93 ST-elevation MI patients with multivessel coronary artery disease.

Disclosures: The COMPLETE optical coherence tomograpy substudy was supported by Abbott Vascular, the Population Health Research Institute, Hamilton Health Sciences, and the Canadian Institutes of Health Research.


Pinilla-Echeverri N. AHA 2019, Late-Breaking Science session 4.