Among patients with type 2 diabetes (T2D) and recent acute coronary syndromes (ACS), average blood pressure (BP) <130/80 mm Hg were associated with worsened cardiovascular (CV) outcomes over the average follow-up period in the EXAMINE trial. The study included 5,380 patients with T2D and recent ACS. Risks of major adverse cardiac events and CV death or heart failure (HF) were analyzed. Researchers found:
- A U-shaped relationship between CV outcomes and BPs was observed.
- Adjusted hazard ratios (HRs) for both major adverse cardiac events and CV death or HF were significantly higher in patients with systolic BPs <130 mm Hg.
- HRs for major adverse cardiac events and for CV death or HF were significantly higher for diastolic BPs <80 mm Hg.
White WB, Jalil F, Cushman WC, et al. Average clinician measured blood pressures and cardiovascular outcomes in patients with type 2 diabetes mellitus and ischemic heart disease in the EXAMINE trial. [Published online ahead of print October 14, 2018]. J Am Heart Assoc. doi:10.1161/JAHA.118.009114.
This Week's Must Reads
Clinician Beliefs on Statins & Patient Adherence, Am J Cardiol; ePub 2019 Jan 4; Lowenstern, et al
Adherence to Statin Therapy in US Adults, J Am Heart Assoc; ePub 2019 Jan 8; Colantonio, et al
Efficacy of Statins for Primary Prevention of CVD, Am Heart J; ePub 2019 Jan 10; Yebyo, et al
Prevalence of FH in Patients with Premature MI, Clin Cardiol; ePub 2019 Jan 13; Cui, Li, et al
Lp(a) Levels & CVD Risk in Patients with Diabetes, Atherosclerosis; ePub 2018 Dec 29; Saeed, et al
Must Reads in Acute Coronary Syndromes
Serum Uric Acid, Silent MI & Mortality, Am J Cardiol; ePub 2018 Dec 19; Ahmad, et al
Treatment Gap in Primary Prevention Patients with ACS, Am J Cardiol; ePub 2018 Nov 7; Bavishi, et al
BP Goals & CV Outcomes in Patients with T2D, J Am Heart Assoc; ePub 2018 Oct 14; White, et al
PCI Trends Among Elderly Patients with ACS, Am J Cardiol; ePub 2018 Sep 27; Elbadawi, et al
Barriers to Healthcare Access After an ACS, Am J Cardiol; ePub 2018 Jul 15; Erskine, et al