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LupusPRO v1.8: Acceptable Reliability, Validity

Lupus; ePub 2017 Oct 31; Azizoddin, et al

LupusPRO v1.8 (including its Sleep, Vitality, and Pain domains) has acceptable reliability and validity, according to a recent evaluation. Use of LupusPRO as an outcome measure in clinical trials, investigators found, would facilitate responsiveness assessment. A total of 131 consecutive systemic lupus erythematosus (SLE) patients (mean age 40.04 [SD=14.10] years) were self-administered surveys assessing fatigue (FACIT, SF-36), pain (Pain Inventory, SF-36), insomnia (Insomnia Severity Index), emotional health (PHQ-9, SF-36) and quality of life (SF-36, LupusPRO) at routine care visits. They found:

  • Scores from the LupusPRO-Sleep domain strongly correlated with insomnia scores, while LupusPRO-Vitality correlated strongly with fatigue (FACIT) and SF-36 vitality.
  • The LupusPRO-Pain domain correlated strongly with pain (SF36 Bodily-Pain, Pain Inventory) scores.
  • Similarly, the LupusPRO domains of Physical and Emotional Health had significant correlations with corresponding SF-36 domains.
Citation:

Azizoddin DR, Weinberg S, Gandhi N, et al. Validation of the LupusPRO version 1.8: an update to a disease-specific patient-reported outcome tool for systemic lupus erythematosus. [Published online ahead of print October 31, 2017]. Lupus. doi:10.1177/0961203317739128.

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