Breast cancer-specific mortality rates were similar in women who received bilateral or unilateral mastectomy, according to a matched cohort analysis involving >41,500 individuals. Participants were diagnosed with unilateral breast cancer between 1998 and 2002. Investigators used a 4-to-1 matched cohort of patients that included ~14,000 patients, and looked at cause-specific death. Among the results:
- 93% of patients had unilateral and the remainder bilateral mastectomy.
- Under 4-to-1 matching, ~11,200 unilateral mastectomy and ~2,800 bilateral mastectomy patients were included.
- Risk of breast cancer-specific death was similar in both groups.
The authors noted that clinicians should consider patient preference and alternative benefits of bilateral mastectomy.
Agarwal S, Pappas L, Agarwal J. Association between unilateral or bilateral mastectomy and breast cancer death in patients with unilateral ductal carcinoma. Cancer Manag Res. 2017;9:649-656. doi:10.2147/CMAR.S148456.
This Week's Must Reads
Advanced Cancer Mortality Predictor Tested, J Oncol Pract; ePub 2017 Dec 5; Adelson, Lee, et al
Impact of Smoke-Free Laws on Lung Cancer Rates, Cancer; ePub 2017 Nov 28; Hahn, Rayens, et al
Racial Disparities in Prostate Cancer Treatment, J Oncol Pract; ePub 2017 Dec 1; Bickell, et al
Oncology PA Burnout, Career Satisfaction Assessed, J Oncol Pract; ePub 2017 Nov 30; Tetzlaff, et al
Improving Patient-Oncologist Shared Decisions, J Oncol Pract; ePub 2017 Nov 27; Tattersall
Must Reads in Breast Cancer
How Negative, Positive Life Events Impact BC Risk, Clin Breast Cancer; ePub 2017 Nov 1; Fischer, et al
Impact of Breast Reconstruction on Weight Change, Plast Reconstr Surg; 2017 Dec; Cho, Shammas, et al
Predicting 21-Gene Recurrence Score Test Uptake, Clin Breast Cancer; 2017 Nov 29; Hull, et al
Unilateral BC: Unilateral or Bilateral Mastectomy?, Cancer Manag Res; 2017 Nov 16; Agarwal, et al
This Can Be Used to Predict Advanced BC Prognosis, Clin Cancer Res; ePub 2017 Nov 27; Rossi, et al