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Unilateral BC: Unilateral or Bilateral Mastectomy?

Cancer Manag Res; 2017 Nov 16; Agarwal, et al

Breast cancer-specific mortality rates were similar in women who received bilateral or unilateral mastectomy, according to a matched cohort analysis involving >41,500 individuals. Participants were diagnosed with unilateral breast cancer between 1998 and 2002. Investigators used a 4-to-1 matched cohort of patients that included ~14,000 patients, and looked at cause-specific death. Among the results:

  • 93% of patients had unilateral and the remainder bilateral mastectomy.
  • Under 4-to-1 matching, ~11,200 unilateral mastectomy and ~2,800 bilateral mastectomy patients were included.
  • Risk of breast cancer-specific death was similar in both groups.

The authors noted that clinicians should consider patient preference and alternative benefits of bilateral mastectomy.

Citation:

Agarwal S, Pappas L, Agarwal J. Association between unilateral or bilateral mastectomy and breast cancer death in patients with unilateral ductal carcinoma. Cancer Manag Res. 2017;9:649-656. doi:10.2147/CMAR.S148456.

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