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Body Composition Status Linked with Migraine Risk

Neurology; ePub 2017 Apr 12; Gelaye, Sacco, et al

The risk of migraine is increased in obese and underweight individuals, according to a recent meta-analysis conducted by 2 independent reviewers. A total of 12 studies, encompassing data from 288,981 unique participants, were included. They found:

  • The age- and sex-adjusted pooled risk of migraine in those with obesity was increased by 27% compared with those of normal weight and remained increased after multivariate adjustments.
  • Although the age- and sex-adjusted pooled migraine risk was increased in overweight individuals, significance was lost after multivariate adjustments.
  • The age- and sex-adjusted pooled risk of migraine in underweight individuals was marginally increased by 13% compared with those of normal weight and remained increased after multivariate adjustments.

Citation:

Gelaye B, Sacco S, Brown WJ, Nitchie HL, Ornello R, Peterlin L. Body composition status and the risk of migraine. A meta-analysis. [Published online ahead of print April 12, 2017]. Neurology. doi:10.1212/WNL.0000000000003919.

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