Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Impact of Heart Failure on Body Composition

Circ Heart Fail; ePub 2017 Sep 12; Forman, et al

In older adults, incident heart failure (HF) was associated with disproportionate loss of lean mass, particularly among men, a recent study found. Using yearly dual-energy x-ray absorptiometry, body composition was assessed among 2,815 participants (48.5% men, 59.6% white, mean age 73.6±2.9 years) from the Health, Aging, and Body Composition study over 6 years, comparing those who developed incident HF vs those who did not. Researchers found:

  • 111 participants developed incident HF over the 6-year study period.
  • At study entry, men and women who later developed HF had higher total body mass vs those who did not develop HF.
  • However, after developing HF, loss of total lean body mass was disproportionate; men with HF lost 654.6 vs 391.4 g/y in non-HF participants.


Forman DE, Santanasto AJ, Boudreau R, et al. Impact of incident heart failure on body composition over time in the Health, Aging, and Body Composition Study population. [Published online ahead of print September 12, 2017]. Circ Heart Fail. doi:10.1161/CIRCHEARTFAILURE.117.003915.

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