Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

CRT Device Choice in Older HF Patients

Am J Cardiol; ePub 2017 Sep 18; Wang, et al

Women are more likely to receive cardiac resynchronization therapy though a pacemaker (CRT-P) than men; and women with CRT, particularly CRT-P, have a better overall survival than men. This according to a recent study that examined the practice of prescribing CRT-P or defibrillator (CRT-D) devices in older women and men with heart failure. 512 CRT recipients (aged ≥75 years, 26% women, 21% CRT-P) were included. Overall survival was compared by gender and type of CRT device implanted. Researchers found:

  • Women were more likely to receive CRT-P vs men (26% vs 19%).
  • Men with CRT-P were significantly older than women with CRT-P and both men and women with CRT-D.
  • Women had lower all-cause mortality compared to men (HR, 0.75), mainly among CRT-P recipients (HR, 0.48); however, this association was diminished after adjusting for differences in patient characteristics (HR, 0.56).

Citation:

Wang Y, Sharbaugh MS, Munir MB, et al. Gender difference in cardiac resynchronization therapy device choice and outcome in heart failure patients ≥75 years of age. [Published online ahead of print September 18, 2017]. Am J Cardiol. doi:10.1016/j.amjcard.2017.08.044.

This Week's Must Reads

Pharmacologic Tx of Seasonal Allergic Rhinitis, Ann Intern Med; ePub 2017 Nov 28; Wallace, et al

Risk of Obesity From Childhood into Adulthood, N Engl J Med; 2017 Nov 30; Ward, Long, et al

Labeling of Selective Androgen Receptor Modulators, JAMA; 2017 Nov 28; Van Wagoner, Eichner, et al

Oral Capsule vs Colonoscopy FMT for CDI, JAMA; 2017 Nov 28; Kao, Roach, et al

HIV Testing & Impact of Delayed Diagnosis, MMWR; 2017 Dec 1; Dailey, Hoots, et al

Must Reads in Cardiology

Racial/Ethnic Disparities in Hospitalization for HF, J Am Heart Assoc; ePub 2017 Nov 16; Dupre, et al

Hospital Readmissions Following HF Hospitalization, JAMA Cardiol; ePub 2017 Nov 12; Gupta, et al

Clinical Predictive Models for Patients with HF, J Am Heart Assoc; ePub 2017 Nov 18; Wessler, et al

Impact of Diabetes Mellitus After LVAD Implantation, Circ Heart Fail; ePub 2017 Nov 15; Asleh, et al

Epidemiology of HF in Older Adults Across Settings , Circ Heart Fail; ePub 2017 Nov 12; Khera, et al