Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

CRT Device Choice in Older HF Patients

Am J Cardiol; ePub 2017 Sep 18; Wang, et al

Women are more likely to receive cardiac resynchronization therapy though a pacemaker (CRT-P) than men; and women with CRT, particularly CRT-P, have a better overall survival than men. This according to a recent study that examined the practice of prescribing CRT-P or defibrillator (CRT-D) devices in older women and men with heart failure. 512 CRT recipients (aged ≥75 years, 26% women, 21% CRT-P) were included. Overall survival was compared by gender and type of CRT device implanted. Researchers found:

  • Women were more likely to receive CRT-P vs men (26% vs 19%).
  • Men with CRT-P were significantly older than women with CRT-P and both men and women with CRT-D.
  • Women had lower all-cause mortality compared to men (HR, 0.75), mainly among CRT-P recipients (HR, 0.48); however, this association was diminished after adjusting for differences in patient characteristics (HR, 0.56).


Wang Y, Sharbaugh MS, Munir MB, et al. Gender difference in cardiac resynchronization therapy device choice and outcome in heart failure patients ≥75 years of age. [Published online ahead of print September 18, 2017]. Am J Cardiol. doi:10.1016/j.amjcard.2017.08.044.

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