Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

No Need to Alter TKI Treatment in These Patients, Am J Hematol; ePub 2017 Oct 13; Alhuraiji, et al

Insurance Subsidy Impact on New TKI Users Assessed, Cancer; ePub 2017 Oct 4; Shen, Zhao, Liu, et al

Ruxolitinib in Patients Who Can’t Take Hydroxyurea, Blood; 2017 Oct 12; Verstovsek, Passamonti, et al

Socioeconomic Status Impact on Chronic GVHD, Biol Blood Marrow Transplant; ePub 2017 Oct 12; Hamilton, et al

Impact of Precision-Dosing Strategy with IVIG, Pharmacotherapy; ePub 2017 Oct 13; Stump, et al

Cardiology

Assessing CCTA for Patients with Suspected CAD, JAMA Intern Med; ePub 2017 Oct 2; Foy, et al

Rivaroxaban + Aspirin for CV Prevention, N Engl J Med; 2017 Oct 5; Eikelboom, et al

Read more in Cardiology

Oncology

Alcohol Use & All-Cause, CV & Ca-Related Mortality, J Am Coll Cardiol; 2017 Aug; Xi, et al

Ovarian Cancer Screening & Mortality, Effect of early detecting and screening studied

Read more in Oncology

Neurology

Exenatide Effects in Patients with Parkinson Disease, Lancet; 2017 Oct 7; Athauda, Maclagan, et al

Orthostatic Hypotension in Middle-Aged Adults, JAMA Intern Med; ePub 2017 Jul 24; Juraschek, et al

Read more in Neurology

Vaccines

Is a Third Dose of MMR Vaccine Needed for Mumps?, N Engl J Med; 2017 Sep 7; Cardemil, et al

New 2017-18 Influenza Vaccine Recommendations, MMWR; ePub 2017 Aug 25; Grohskopf, et al

Read more in Vaccines

Obesity

Metabolic Outcomes After Gastric Bypass Surgery, N Engl J Med; 2017 Sep 21; Adams, et al

Weight Gain & Odds of Healthy Aging, JAMA; 2017 Jul 18; Zheng, Manson, et al

Read more in Obesity

AML

Cochrane on Value of TPO Mimetics for MDS, Cochrane; 2017 Sep 29; Dodillet, Kreuzer, et al

Allo-HSCT for Mixed Phenotype Acute Leukemia, Haematologica; ePub 2017 Sep 29; Munker, et al

Read more in AML

Health Policy

FDA Approval of Intragastric Balloon System, Device assists adults with weight management

FDA Approval for Balloon Device, Non-surgical device treats obesity

Read more in Health Policy

Nephrology

BP Control & Risk of Mortality in Patients with CKD, JAMA Intern Med; ePub 2017 Sep 5; Malhotra, et al

Intensive SBP Lowering & Kidney, CV Outcomes, Ann Intern Med; ePub 2017 Sep 5; Beddhu, et al

Read more in Nephrology

Hepatitis

COBAS Diagnostic Gets Expanded Indication, Roche news release; 2016 March 21

Sofosbuvir Regimens in Liver Decompensation, J Viral Hepat; ePub 2016 Mar 17; Perumalswami, et al

Read more in Hepatitis

Women's Health

Lifestyle Risk Factors & Hypertension in Women, BMJ; ePub 2017 Jul 12; Timpka, Stuart, et al

Maternal Use of Oral Contraceptives, Is there a risk of birth defects?

Read more in Women's Health

Sexual Health

Treating Urogenital Chlamydia Infection, Is doxycycline superior to azithromycin?

FDA Approves Sexual Desire Disorder Drug, Flibanserin (Addyi) approved to treat premenopausal women

Read more in Sexual Health

Dermatology

Pubic Hair Grooming-Related Injuries Evaluated, JAMA Dermatol; ePub 2017 Aug 16; Truesdale, et al

Atopic Dermatitis in Children , Putting guidelines into primary practice

Read more in Dermatology