Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

Driver Mutations and Prognosis in PMF Assessed, Am J Hematol; ePub 2017 November 22; Tefferi, et al

Symptom Burden in People with MF, Thrombocytopenia, Leuk Res; 2017 Dec; Scotch, Kosiorek, et al

Consider This Method to Measure JAK2 Status in MF, Leuk Res; 2017 Dec; Strati, Benton, et al

Ruxolitinib + Azacytidine in MDS/MPNs Evaluated, Am J Hematol; ePub 2017 Nov 14; Assi, et al

Reappraising the Approach to PV and ET, Curr Opin Hematol; ePub 2017 Nov 30; Vannucchi, et al

Clinical Guidelines

ACP Guideline for HBV Vaccination & Screening, Ann Intern Med; ePub 2017 Nov 21; Abara, et al

AHA/ACC Issues New Hypertension Guideline, Hypertension; ePub 2017 Nov 13; Whelton, et al

Read more in Clinical Guidelines

Cardiology

Racial/Ethnic Disparities in Hospitalization for HF, J Am Heart Assoc; ePub 2017 Nov 16; Dupre, et al

Hospital Readmissions Following HF Hospitalization, JAMA Cardiol; ePub 2017 Nov 12; Gupta, et al

Read more in Cardiology

Oncology

Weight Loss Diets & All-Cause Mortality, BMJ; ePub 2017 Nov 14; Ma, Avenell, et al

Cancer Risk in Overweight & Obese Individuals, MMWR; ePub 2017 Oct 3; Steele, et al

Read more in Oncology

Neurology

Methylphenidate for Apathy in Alzheimer’s Disease, Am J Psychiatry; ePub 2017 Sep 15; Padala, et al

Exenatide Effects in Patients with Parkinson Disease, Lancet; 2017 Oct 7; Athauda, Maclagan, et al

Read more in Neurology

Geriatrics

Methylphenidate for Apathy in Alzheimer’s Disease, Am J Psychiatry; ePub 2017 Sep 15; Padala, et al

Bisphosphonate Use & Fractures in Older Women, J Am Geriatr Soc; 2017 Sep; Drieling, et al

Read more in Geriatrics

Obesity

Weight Loss Diets & All-Cause Mortality, BMJ; ePub 2017 Nov 14; Ma, Avenell, et al

Cancer Risk in Overweight & Obese Individuals, MMWR; ePub 2017 Oct 3; Steele, et al

Read more in Obesity

AML

Azacitidine in Lower-Risk MDS Shows Promise, Oncologist; ePub 2017 Nov 8; Komrokji, et al

Clostridium Difficile Infection in People with MDS, World J Clin Oncol; 2017 Oct 10; Shaht, et al

Read more in AML

Health Policy

FDA Approval of Intragastric Balloon System, Device assists adults with weight management

FDA Approval for Balloon Device, Non-surgical device treats obesity

Read more in Health Policy

Nephrology

BP Control & Risk of Mortality in Patients with CKD, JAMA Intern Med; ePub 2017 Sep 5; Malhotra, et al

Intensive SBP Lowering & Kidney, CV Outcomes, Ann Intern Med; ePub 2017 Sep 5; Beddhu, et al

Read more in Nephrology

Hepatitis

COBAS Diagnostic Gets Expanded Indication, Roche news release; 2016 March 21

Sofosbuvir Regimens in Liver Decompensation, J Viral Hepat; ePub 2016 Mar 17; Perumalswami, et al

Read more in Hepatitis

Women's Health

Pesticide Residue Intake in Pregnancy Outcomes, JAMA Intern Med; ePub 2017 Oct 30; Chiu, et al

Bisphosphonate Use & Fractures in Older Women, J Am Geriatr Soc; 2017 Sep; Drieling, et al

Read more in Women's Health

Sexual Health

Treating Urogenital Chlamydia Infection, Is doxycycline superior to azithromycin?

FDA Approves Sexual Desire Disorder Drug, Flibanserin (Addyi) approved to treat premenopausal women

Read more in Sexual Health

Dermatology

Pubic Hair Grooming-Related Injuries Evaluated, JAMA Dermatol; ePub 2017 Aug 16; Truesdale, et al

Atopic Dermatitis in Children , Putting guidelines into primary practice

Read more in Dermatology