Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

LAMA + LABA for Patients with Stable COPD, JAMA; 2017 Oct 3; Horita, Nagashima, et al

Assessing CCTA for Patients with Suspected CAD, JAMA Intern Med; ePub 2017 Oct 2; Foy, et al

Rivaroxaban + Aspirin for CV Prevention, N Engl J Med; 2017 Oct 5; Eikelboom, et al

Exenatide Effects in Patients with Parkinson Disease, Lancet; 2017 Oct 7; Athauda, Maclagan, et al

FDA Approves Fast-Acting Mealtime Insulin, Novo Nordisk news release; 2017 Sep 29

Mental Health

Spatial Distribution of Pain After Weight Loss, J Pain; ePub 2017 Aug 25; Schrepf, et al

Cannabis for the Treatment of Chronic Pain, Ann Intern Med; ePub 2017 Aug 15; Nugent, et al

Read more in Mental Health

Geriatrics

Comparing Group Exercise Programs in Older Adults , JAMA Intern Med; ePub 2017 Aug 14; Brach, et al

Deaths from Alzheimer’s Disease in the US, MMWR; 2017 May 26; Taylor, Greenlund, et al

Read more in Geriatrics

Pediatrics

Early-Life Environmental Asthma Risk in Children, J Allergy Clin Immunol; ePub 2017 Sep 19; O’Connor, et al

Breastfeeding & Reduced Risk of Peanut Sensitization, J Allergy Clin Immunol; ePub 2017 Sep 12; Pitt, et al

Read more in Pediatrics

Cardiology

Assessing CCTA for Patients with Suspected CAD, JAMA Intern Med; ePub 2017 Oct 2; Foy, et al

Rivaroxaban + Aspirin for CV Prevention, N Engl J Med; 2017 Oct 5; Eikelboom, et al

Read more in Cardiology

Asthma

Early-Life Environmental Asthma Risk in Children, J Allergy Clin Immunol; ePub 2017 Sep 19; O’Connor, et al

Tezepelumab and Uncontrolled Asthma in Adults , N Engl J Med; ePub 2017 Sep 7; Corren, et al

Read more in Asthma

Oncology

Alcohol Use & All-Cause, CV & Ca-Related Mortality, J Am Coll Cardiol; 2017 Aug; Xi, et al

Guideline Quality for Care of Cancer Survivors, JAMA Intern Med; 2017 May; Merkow, et al

Read more in Oncology

Rheumatology

Risk of NSAID Toxicity in Patients with Arthritis, Am J Med; ePub 2017 Jul 26; Solomon, et al

Intra-Articular Triamcinolone for Knee Osteoarthritis, JAMA; 2017 May 16; McAlindon, LaValley, et al

Read more in Rheumatology

Vaccines

Is a Third Dose of MMR Vaccine Needed for Mumps?, N Engl J Med; 2017 Sep 7; Cardemil, et al

New 2017-18 Influenza Vaccine Recommendations, MMWR; ePub 2017 Aug 25; Grohskopf, et al

Read more in Vaccines

Men's Health

CV Toxicity of Illicit Anabolic-Androgenic Steroid Use, Circulation; ePub 2017 May 22; Baggish, et al

USPSTF Update: Screening for Prostate Cancer, JAMA; ePub 2017 Apr 11; Bibbins-Domingo, et al

Read more in Men's Health

Obesity

Metabolic Outcomes After Gastric Bypass Surgery, N Engl J Med; 2017 Sep 21; Adams, et al

Weight Gain & Odds of Healthy Aging, JAMA; 2017 Jul 18; Zheng, Manson, et al

Read more in Obesity

Neurology

Exenatide Effects in Patients with Parkinson Disease, Lancet; 2017 Oct 7; Athauda, Maclagan, et al

Orthostatic Hypotension in Middle-Aged Adults, JAMA Intern Med; ePub 2017 Jul 24; Juraschek, et al

Read more in Neurology

Preventive Care

Sedentary Behavior and Mortality in Older Adults, Ann Intern Med; ePub 2017 Sep 12; Diaz, et al

Do Patient Beliefs Impact Medication Adherence?, J Am Board Fam Med; 2017 May-Jun; Gagnon, et al

Read more in Preventive Care

Health Policy

Postmarket Safety Events After FDA Approvals, JAMA; 2017 May 9; Downing, Shah, et al

FDA Approval of Intragastric Balloon System, Device assists adults with weight management

Read more in Health Policy