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Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Recommendations for Managing Acne Fulminans

J Am Acad Dermatol; 2017 Jul; Greywal, et al

In order to better define the spectrum of acne fulminans (AF) and its variants, devise optimal therapeutic approaches, and identify areas of future research, appropriate clinical case presentations and consensus survey questions were recently utilized to create final recommendations based on both the literature and the expert consensus. AF is a severe variant of inflammatory acne that typically manifests as an explosive worsening and ulceration of skin lesions, and can be associated with systemic symptoms. However, there is a paucity of evidence-based information and no clear guidelines concerning the classification and treatment of AF. A panel of physicians with expertise in severe acne vulgaris was convened after a comprehensive literature review of severe acne variants. Priority topics were reviewed and presented by each panelist at a 5-hour conference. These guidelines better characterize AF and provide health care practitioners approaches to the classification, treatment, and prevention of AF and its variants.


Greywal T, Zaenglein AL, Baldwin HE, et al. Evidence-based recommendations for the management of acne fulminans and its variants. J Am Acad Dermatol. 2017;77(1): 109-117. doi:10.1016/j.jaad.2016.11.028.

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