Conference Coverage

Vitality predicts T2DM major cardiovascular event risk


Key clinical point: Two simple questions about vitality could help assess the risk of major cardiovascular events in patients with type 2 diabetes mellitus.

Major finding: The hazard ratios for seldom feeling “full of pep” and seldom having “lots of energy” and MACE were a respective 1.31 (P = .003) and 1.44 (P less than .0001).

Data source: A prospective, observational primary care study of 761 patients with type 2 diabetes mellitus.

Disclosures: The presenting author had no relevant financial disclosures.


AT EASD 2017


Assessing type 2 diabetes mellitus patients’ sense of vitality may help predict whether they will experience a major cardiovascular event,according to the results of a primary care study.

Seldom feeling “full of pep” or not having “a lot of energy” was associated with an increased risk of a major cardiovascular event (MACE) in middle-aged (55-66 years) adults with T2DM, Marta Vergara, MD, reported at the annual meeting of the European Association for the Study of Diabetes.

Dr. Marta Vergara of Linköping University (Sweden)
Dr. Marta Vergara
In fact, there was a 32% and a 44% increased risk of MACE in those who answered that they rarely felt full of pep or rarely had a lot of energy, she said, with respective hazard ratios (HRs) of 1.32 (P = .003 ) and 1.44 (P less than .0001). The risk remained after adjustment for multiple confounding factors.

“It’s well known that patients with type 2 diabetes have a high risk for developing cardiovascular disease, and it is the main cause of death,” said Dr. Vergara of Linköping (Sweden) University.

While several risk factors for cardiovascular disease are known and widely monitored for in clinical practice worldwide, including psychological aspects such as mental stress, ways to identify patients earlier are needed.

“We need more clinically useful and easy-to-manage measurement instruments,” Dr. Vergara said.

Using data from the ongoing Cardiovascular Risk Factors in Patients With Diabetes – a Prospective Study in Primary Care (CARDIPP), Dr. Vergara and colleagues identified two questions used in the 36-Item Short Form (SF-36) that might fit the bill:
  • ”How much time during the past 4 weeks did you feel full of pep?”
  • “How much time during the past 4 weeks did you have a lot of energy?”

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